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| Weekly Wellness Brief Medication Orders Shift After White House Autism Briefing A new analysis found that hospital orders for acetaminophen among pregnant patients declined after a 2025 White House announcement, while leucovorin prescriptions for children rose sharply. | |
| Key Takeaways |
| Acetaminophen orders fell Orders in emergency rooms for pregnant patients dropped 10% in the weeks after the September briefing. | | | Leucovorin prescriptions jumped Outpatient prescriptions for children ages 5 to 17 increased sharply, more than doubling in week two. | | | Researchers note influence Authors said the data show how quickly statements from public officials may affect health care behavior. | | |
| In Detail |
| ER Medication Trends Shifted Following Federal Autism Announcement Researchers from Harvard and Brown analyzed more than 294 million patient records from hospitals and clinics across the U.S. to examine prescribing patterns after a September 2025 White House briefing. |  | | The study found that acetaminophen orders for pregnant patients in emergency rooms fell 10% between Sept. 22 and Dec. 7, 2025, after the White House linked use during pregnancy to a higher autism risk. Orders dropped 16% in the first month and reached a low point of 20% in the third week before gradually returning toward expected levels by early December. The authors noted the analysis did not include over-the-counter acetaminophen purchases, which remain the most common way the medication is used. |  | | During the same period, outpatient prescriptions for leucovorin in children ages 5 to 17 rose significantly after the administration announced plans to begin the approval process for the drug as a possible autism treatment. The analysis showed a 93% increase in the first month, a 113% spike in week two, and an overall rise of about 71% through early December. Leucovorin is typically used to treat folate deficiency and reduce side effects from some chemotherapy drugs, and while it has been studied for certain children with autism and cerebral folate deficiency, experts say its broader role in autism care remains unclear. | | | |
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